Linked Life Data

11123220

Source:http://linkedlifedata.com/resource/pubmed/id/11123220

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:11123220rdf:typepubmed:Citationlld:pubmed
pubmed-article:11123220lifeskim:mentionsumls-concept:C1135183lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C0026820lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C0205042lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C0025219lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C0036751lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C0205409lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C1704632lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C0871261lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C2911692lld:lifeskim
pubmed-article:11123220lifeskim:mentionsumls-concept:C1706817lld:lifeskim
pubmed-article:11123220pubmed:issue1lld:pubmed
pubmed-article:11123220pubmed:dateCreated2001-2-2lld:pubmed
pubmed-article:11123220pubmed:abstractTextThe present study was designed to determine the effects of melatonin on coronary vasomotor tone. Porcine coronary arteries were suspended in organ chambers for isometric tension recording. Melatonin (10(-10)-10(-5) M) itself caused neither contraction nor relaxation of the tissues. Serotonin (10(-9)-10(-5) M) caused concentration-dependent contractions of coronary arteries, and in the presence of melatonin (10(-7) M) the maximal response to serotonin was increased in rings with but not without endothelium. In contrast, melatonin had no effect on contractions produced by the thromboxane A(2) analog U-46619 (10(-10)-10(-7) M). The melatonin-receptor antagonist S-20928 (10(-6) M) abolished the potentiating effect of melatonin on serotonin-induced contractions in endothelium-intact coronary arteries, as did treatment with 1H-[1, 2,4]oxadiazolo[4,3-a]quinoxalin-1-one (10(-5) M), methylene blue (10(-5) M), or N(G)-nitro-L-arginine (3 x 10(-5) M). In tissues contracted with U-46619, serotonin caused endothelium-dependent relaxations that were inhibited by melatonin (10(-7) M). Melatonin also inhibited coronary artery relaxation induced by sodium nitroprusside (10(-9)-10(-5) M) but not by isoproterenol (10(-9)-10(-5) M). These results support the hypothesis that melatonin, by inhibiting the action of nitric oxide on coronary vascular smooth muscle, selectively potentiates the vasoconstrictor response to serotonin in coronary arteries with endothelium.lld:pubmed
pubmed-article:11123220pubmed:languageenglld:pubmed
pubmed-article:11123220pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:citationSubsetIMlld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:11123220pubmed:statusMEDLINElld:pubmed
pubmed-article:11123220pubmed:monthJanlld:pubmed
pubmed-article:11123220pubmed:issn0363-6135lld:pubmed
pubmed-article:11123220pubmed:authorpubmed-author:VanhoutteP...lld:pubmed
pubmed-article:11123220pubmed:authorpubmed-author:YanoYYlld:pubmed
pubmed-article:11123220pubmed:authorpubmed-author:ScalbertEElld:pubmed
pubmed-article:11123220pubmed:authorpubmed-author:O'RourkeS TSTlld:pubmed
pubmed-article:11123220pubmed:authorpubmed-author:DelagrangePPlld:pubmed
pubmed-article:11123220pubmed:issnTypePrintlld:pubmed
pubmed-article:11123220pubmed:volume280lld:pubmed
pubmed-article:11123220pubmed:ownerNLMlld:pubmed
pubmed-article:11123220pubmed:authorsCompleteYlld:pubmed
pubmed-article:11123220pubmed:paginationH76-82lld:pubmed
pubmed-article:11123220pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:meshHeadingpubmed-meshheading:11123220...lld:pubmed
pubmed-article:11123220pubmed:year2001lld:pubmed
pubmed-article:11123220pubmed:articleTitleMelatonin potentiates contractile responses to serotonin in isolated porcine coronary arteries.lld:pubmed
pubmed-article:11123220pubmed:affiliationDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58105, USA.lld:pubmed
pubmed-article:11123220pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11123220pubmed:publicationTypeIn Vitrolld:pubmed
pubmed-article:11123220pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:11123220lld:pubmed