11122802

Source:http://linkedlifedata.com/resource/pubmed/id/11122802

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0013203, umls-concept:C0441712, umls-concept:C1516465, umls-concept:C1533691
pubmed:dateCreated	2001-1-26
pubmed:abstractText	This article reviews the cellular mechanisms that confer biochemical and clinical resistance to antineoplastic agents used in the adjunctive treatment and palliation of metastatic ovarian cancer. The historical development of in vitro chemosensitivity testing is also reviewed, along with published experiences of various investigators with assays used in clinical ovarian cancer treatment programs. Finally, an investigational protocol for chemosensitivity testing is proposed.
pubmed:language	eng
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:author	pubmed-author:ManettaAA, pubmed-author:TewariKK
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	77-84
pubmed:dateRevised	2005-11-16
pubmed:meshHeading	pubmed-meshheading:11122802-Drug Resistance, Neoplasm, pubmed-meshheading:11122802-Drug Screening Assays, Antitumor, pubmed-meshheading:11122802-Female, pubmed-meshheading:11122802-Humans, pubmed-meshheading:11122802-Ovarian Neoplasms, pubmed-meshheading:11122802-Sensitivity and Specificity
pubmed:articleTitle	In vitro chemosensitivity testing and mechanisms of drug resistance.
pubmed:affiliation	Division of Oncology, Chao Family Comprehensive Cancer Center, University of Califorinia, Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA.
pubmed:publicationType	Journal Article, Review