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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-1-18
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pubmed:abstractText |
The aroC gene of the facultative intracellular pathogen Brucella suis was cloned and sequenced. The cloned aroC gene complements Escherichia coli and Salmonella enterica serovar Typhimurium aroC mutants. A B. suis aroC mutant was found to be unable to grow in a defined medium without aromatic compounds. The mutant was highly attenuated in tissue culture (THP1 macrophages and HeLa cells) and murine virulence models.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-10678941,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-14848423,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-1759503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-2106482,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-2182772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-2185782,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-2266855,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-2777382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-3058818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-3276625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-3291451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-7015147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-7559411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-7618105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-7642258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-7927667,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-8068328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-8359896,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-8675325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-9172844,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-9405209,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-9453608,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-9466259,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-9655396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-9916080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11119550-9930696
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
547-50
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:11119550-Animals,
pubmed-meshheading:11119550-Brucella,
pubmed-meshheading:11119550-Cloning, Molecular,
pubmed-meshheading:11119550-Culture Media,
pubmed-meshheading:11119550-HeLa Cells,
pubmed-meshheading:11119550-Humans,
pubmed-meshheading:11119550-Mice,
pubmed-meshheading:11119550-Mice, Inbred BALB C,
pubmed-meshheading:11119550-Mutation,
pubmed-meshheading:11119550-Phosphorus-Oxygen Lyases,
pubmed-meshheading:11119550-Virulence
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pubmed:year |
2001
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pubmed:articleTitle |
Aromatic compound-dependent Brucella suis is attenuated in both cultured cells and mouse models.
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pubmed:affiliation |
INSERM U431, Faculté de Médecine, 30900 Nîmes, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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