Linked Life Data

11117665

Source:http://linkedlifedata.com/resource/pubmed/id/11117665

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-12-14
pubmed:abstractText
The long-term consequences of intra-uterine growth retardation (IUGR) on postnatal growth and development are well known. More recently, several epidemiological and clinical studies in adults have provided evidence that low birth weight is an independent risk factor for the syndrome of insulin resistance in mid to late adulthood. In the present study, we demonstrated that individuals born small for gestational age showed isolated insulin resistance in early adulthood with no impairment of serum lipid concentrations and blood pressure at this age. Angiotensin-I converting enzyme gene polymorphism has also been shown to modulate the effect on insulin resistance of being small for gestational age. Fetal malnutrition may be the critical factor to explain the relationship between IUGR and insulin resistance which might be modulated by genetic factors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0334-018X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13 Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1257-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Syndrome X: a consequence of intra-uterine malnutrition?
pubmed:affiliation
Pediatric Endocrinology-Diabetes Unit, INSERM U 457, H pital Robert Debré, Paris, France. juliane.leger@rdb.ap-hop-paris.fr
pubmed:publicationType
Journal Article