Source:http://linkedlifedata.com/resource/pubmed/id/11115688
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7-8
|
pubmed:dateCreated |
2001-2-2
|
pubmed:abstractText |
The aim of the present study was to evaluate the persistence of anti-hepatitis B protective levels in young patients with type 1 diabetes, successfully immunised with a recombinant hepatitis B vaccine. We re-evaluated, after a 4 year follow-up, 54 patients and 70 age and sex-matched healthy subjects. Protective antibodies levels were found in 50/54 (92%) patients and in 67/70 (96%) controls. Moreover, anti-HBs levels were similar in diabetic patients and controls (means of log-titre and (sd); 1.95 (0.88) and 2.18 (0.64) patients and controls, respectively; P=0.11). No cases of clinical hepatitis were reported and all patients and controls remained HBc negative. These data demonstrate the persistence of anti-HBs levels in children, adolescents and young patients with type 1 diabetes after recombinant hepatitis B vaccine showing evidence of longterm immunogenity and protective effect.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0264-410X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
22
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
680-3
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:11115688-Adolescent,
pubmed-meshheading:11115688-Adult,
pubmed-meshheading:11115688-Case-Control Studies,
pubmed-meshheading:11115688-Child,
pubmed-meshheading:11115688-Diabetes Mellitus, Type 1,
pubmed-meshheading:11115688-Female,
pubmed-meshheading:11115688-Follow-Up Studies,
pubmed-meshheading:11115688-Hepatitis B,
pubmed-meshheading:11115688-Hepatitis B Antibodies,
pubmed-meshheading:11115688-Hepatitis B Vaccines,
pubmed-meshheading:11115688-Humans,
pubmed-meshheading:11115688-Male,
pubmed-meshheading:11115688-Time Factors,
pubmed-meshheading:11115688-Vaccines, Synthetic
|
pubmed:year |
2000
|
pubmed:articleTitle |
Long term persistence of anti-HBs protective levels in young patients with type 1 diabetes after recombinant hepatitis B vaccine.
|
pubmed:affiliation |
Department of Pediatrics, University of Pavia, IRCCS Policlinico S. Matteo, P.le Golgi 2, 27100, Pavia, Italy. gl.marseglia@smatteo.pv.it
|
pubmed:publicationType |
Journal Article
|