Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-3-13
pubmed:abstractText
An abnormal vascular status is present in the transplanted kidney. To define whether vascular factors might influence kidney function of the graft, the renal volume, blood flow and vascular resistance of a group of healthy subjects were compared with those of a group of well functioning renal transplants by color Doppler ultrasonography. Sixty healthy subjects and 75 well functioning cadaver renal transplant recipients were compared by color Doppler ultrasonography. Subsequently, 15 couples of donors and recipients of a living related renal graft were compared to observe the differences between the two organs of the same subject in a different environment. The variables studied were: the diameters and the volume of the kidney, renal blood flow and renal resistance index (RI). The group of cadaver renal transplant patients showed higher mean blood pressure (P = 0.009), higher serum creatinine levels (P = 0.0001) and lower endogenous creatinine clearance (P < 0.0001) than healthy controls. The length (P < 0.00001) and volume (P < 0.001) of the kidneys of cadaver transplanted patients were significantly greater than those of healthy subjects, while the length and volume of the living donors kidneys were identical to those of the recipients. RI, measured on renal vessels, showed lower values in healthy subjects and in kidney donors than in transplanted patients (P < 0.00001). Well functioning transplanted kidneys showed increased renal arterial RI. This non-immunologic factor did not appear to be detrimental with renal function in time, at least until 50 months after successful grafting.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0934-0874
pubmed:author
pubmed:issnType
Print
pubmed:volume
13 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S84-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11111969-Adult, pubmed-meshheading:11111969-Azathioprine, pubmed-meshheading:11111969-Blood Pressure, pubmed-meshheading:11111969-Cadaver, pubmed-meshheading:11111969-Cyclosporine, pubmed-meshheading:11111969-Female, pubmed-meshheading:11111969-Graft Survival, pubmed-meshheading:11111969-Humans, pubmed-meshheading:11111969-Immunosuppressive Agents, pubmed-meshheading:11111969-Kidney, pubmed-meshheading:11111969-Kidney Transplantation, pubmed-meshheading:11111969-Living Donors, pubmed-meshheading:11111969-Male, pubmed-meshheading:11111969-Middle Aged, pubmed-meshheading:11111969-Reference Values, pubmed-meshheading:11111969-Regional Blood Flow, pubmed-meshheading:11111969-Renal Circulation, pubmed-meshheading:11111969-Tissue Donors, pubmed-meshheading:11111969-Treatment Outcome, pubmed-meshheading:11111969-Ultrasonography, Doppler, Color, pubmed-meshheading:11111969-Vascular Resistance
pubmed:year
2000
pubmed:articleTitle
Effect of increased arterial resistance index on long-term outcome of well-functioning kidney grafts.
pubmed:affiliation
Divisione di Nefrologia e Dialisi, IRCCS Ospedale Maggiore di Milano, Italy.
pubmed:publicationType
Journal Article, Comparative Study