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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2001-3-13
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pubmed:abstractText |
Histopathological findings in renal allograft with stable function remain unclear. We therefore performed non-episode biopsy in the long-surviving renal allograft to investigate the histopathological changes. Our data show that, although arteriolopathy is characteristic of drug-induced nephropathy, it is unrelated to dosage and concentration of cyclosporine or tacrolimus in non-episode biopsy. We evaluated therefore the clinicopathological findings of arteriolopathy in this study. Non-episode biopsy was defined as follows: as serum creatinine level lower than, 2.0 mg/dl and a urinary protein level lower than 500 mg/day. A total of 65 biopsy specimens were enrolled in this study as non-episode biopsy. Twenty-nine specimens revealed arteriolopathy. There were no statistically significant differences between arteriolopathy and dosage or concentration of cyclosporine or tacrolimus. Arteriolopathy in non-episode biopsy was related to time of biopsy, kidney age, hypertension, and hyperlipidemia, suggesting that it is important for graft survival to strictly control blood pressure and blood lipid level.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0934-0874
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pubmed:author |
pubmed-author:GestHH,
pubmed-author:HatoriMM,
pubmed-author:IchimaruNN,
pubmed-author:ImaiEE,
pubmed-author:InoueTT,
pubmed-author:KameokaHH,
pubmed-author:KojimaYY,
pubmed-author:KokadoYY,
pubmed-author:KyakunoMM,
pubmed-author:KyoMM,
pubmed-author:MiyamotoMM,
pubmed-author:MorozumiKK,
pubmed-author:NakamuraTT,
pubmed-author:OkiCC,
pubmed-author:OkuyamaAA,
pubmed-author:PermpongkosolSS,
pubmed-author:TakaharaSS,
pubmed-author:TanakaTT,
pubmed-author:TojoRR,
pubmed-author:WangJ DJD
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pubmed:issnType |
Print
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pubmed:volume |
13 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S73-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11111966-Adult,
pubmed-meshheading:11111966-Arterioles,
pubmed-meshheading:11111966-Biopsy,
pubmed-meshheading:11111966-Blood Pressure,
pubmed-meshheading:11111966-Cholesterol,
pubmed-meshheading:11111966-Creatinine,
pubmed-meshheading:11111966-Cyclosporine,
pubmed-meshheading:11111966-Female,
pubmed-meshheading:11111966-Graft Rejection,
pubmed-meshheading:11111966-Graft Survival,
pubmed-meshheading:11111966-Humans,
pubmed-meshheading:11111966-Hypertension,
pubmed-meshheading:11111966-Kidney Transplantation,
pubmed-meshheading:11111966-Living Donors,
pubmed-meshheading:11111966-Male,
pubmed-meshheading:11111966-Survivors,
pubmed-meshheading:11111966-Tacrolimus,
pubmed-meshheading:11111966-Transplantation, Homologous,
pubmed-meshheading:11111966-Triglycerides
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pubmed:year |
2000
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pubmed:articleTitle |
Clinicopathological evaluation in non-episode biopsies of renal transplant allograft.
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pubmed:affiliation |
Department of Urology, Osaka University Medical School, Suita-City, Japan.
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pubmed:publicationType |
Journal Article
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