Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-12-28
pubmed:abstractText
The rare MNS antigen Or (MNS31) is sensitive to ficin, papain and sialidase, but partially resistant to trypsin (0.05%); the effect of alpha-chymotrypsin is not known. A point mutation, 204C --> T in exon 3 of GYPA, is associated with the Or+ phenotype. We report here the first case of hemolytic disease of the newborn (HDN) caused by anti-Or, and expand the information on the nature of the Or determinant.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0042-9007
pubmed:author
pubmed:copyrightInfo
Copyright 2000 S. Karger AG, Basel
pubmed:issnType
Print
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
180-2
pubmed:dateRevised
2009-1-8
pubmed:meshHeading
pubmed-meshheading:11111238-Adult, pubmed-meshheading:11111238-Amino Acid Substitution, pubmed-meshheading:11111238-Chymotrypsin, pubmed-meshheading:11111238-Coombs' Test, pubmed-meshheading:11111238-DNA Mutational Analysis, pubmed-meshheading:11111238-Dithiothreitol, pubmed-meshheading:11111238-Epitopes, pubmed-meshheading:11111238-Erythroblastosis, Fetal, pubmed-meshheading:11111238-Erythrocyte Membrane, pubmed-meshheading:11111238-Female, pubmed-meshheading:11111238-Glycophorin, pubmed-meshheading:11111238-Humans, pubmed-meshheading:11111238-Infant, Newborn, pubmed-meshheading:11111238-Isoantibodies, pubmed-meshheading:11111238-MNSs Blood-Group System, pubmed-meshheading:11111238-Male, pubmed-meshheading:11111238-Maternal-Fetal Exchange, pubmed-meshheading:11111238-Papain, pubmed-meshheading:11111238-Phenotype, pubmed-meshheading:11111238-Point Mutation, pubmed-meshheading:11111238-Pregnancy, pubmed-meshheading:11111238-Trypsin
pubmed:year
2000
pubmed:articleTitle
First example of hemolytic disease of the newborn caused by anti-Or and confirmation of the molecular basis of Or.
pubmed:affiliation
New York Blood Center, New York, NY 10021, USA. mreid@nybc.org
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Case Reports