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pubmed-article:11106377pubmed:dateCreated2001-1-16lld:pubmed
pubmed-article:11106377pubmed:abstractTextWe describe here the isolation and cytogenetic characterization of a mutation inseparabile which generates in males a high frequency of A-X females. The mutation, segregating in low frequency in a laboratory stock, maps to cytological location 82F7-11 in the third chromosome. The mutation acts premeiotically in the male germ line. Disrupting the X chromosome centromeric heterochromatin suppresses the formation of A-X chromosome, implying that the mutation is involved in chromatid cohesion. The inseparabile mutation also affects disjunction of the chromosome 4 in males. We suspect that the mutation was responsible for the original A-X female found by L. V. Morgan in 1921.lld:pubmed
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pubmed-article:11106377pubmed:authorpubmed-author:GreenM MMMlld:pubmed
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pubmed-article:11106377pubmed:pagination14484-7lld:pubmed
pubmed-article:11106377pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:11106377pubmed:articleTitleOn the origin of metacentric, attached-X (A-X) chromosomes in Drosophila melanogaster males.lld:pubmed
pubmed-article:11106377pubmed:affiliationSection of Molecular and Cellular Biology, University of California, Davis, CA 95616, USA.lld:pubmed
pubmed-article:11106377pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11106377pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
pubmed-article:11106377pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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