Linked Life Data

11106377

Source:http://linkedlifedata.com/resource/pubmed/id/11106377

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
26
pubmed:dateCreated
2001-1-16
pubmed:abstractText
We describe here the isolation and cytogenetic characterization of a mutation inseparabile which generates in males a high frequency of A-X females. The mutation, segregating in low frequency in a laboratory stock, maps to cytological location 82F7-11 in the third chromosome. The mutation acts premeiotically in the male germ line. Disrupting the X chromosome centromeric heterochromatin suppresses the formation of A-X chromosome, implying that the mutation is involved in chromatid cohesion. The inseparabile mutation also affects disjunction of the chromosome 4 in males. We suspect that the mutation was responsible for the original A-X female found by L. V. Morgan in 1921.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
97
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
14484-7
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
On the origin of metacentric, attached-X (A-X) chromosomes in Drosophila melanogaster males.
pubmed:affiliation
Section of Molecular and Cellular Biology, University of California, Davis, CA 95616, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't