Source:http://linkedlifedata.com/resource/pubmed/id/11106325
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2000-12-26
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pubmed:abstractText |
The use of sensitive molecular techniques to detect rare cells in a population is of increasing interest to the molecular pathologist, but detection limits often are poorly defined in any given molecular assay. We combined the approaches of real-time quantitative PCR with ARMS(TM) allele-specific amplification in a novel assay for detecting mutant K-ras sequences in clinical samples.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0009-9147
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1929-38
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11106325-Alleles,
pubmed-meshheading:11106325-Codon,
pubmed-meshheading:11106325-Humans,
pubmed-meshheading:11106325-Lung Neoplasms,
pubmed-meshheading:11106325-Nucleic Acid Amplification Techniques,
pubmed-meshheading:11106325-Point Mutation,
pubmed-meshheading:11106325-Tumor Markers, Biological,
pubmed-meshheading:11106325-ras Proteins
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pubmed:year |
2000
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pubmed:articleTitle |
K-ras point mutation detection in lung cancer: comparison of two approaches to somatic mutation detection using ARMS allele-specific amplification.
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pubmed:affiliation |
AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom. simon.clayton@astrazeneca.com
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pubmed:publicationType |
Journal Article,
Comparative Study
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