rdf:type |
|
lifeskim:mentions |
umls-concept:C0008976,
umls-concept:C0009402,
umls-concept:C0016360,
umls-concept:C0022277,
umls-concept:C0034656,
umls-concept:C0123931,
umls-concept:C0205179,
umls-concept:C0205390,
umls-concept:C0585332,
umls-concept:C0677667,
umls-concept:C0679729,
umls-concept:C1511237,
umls-concept:C1518578,
umls-concept:C1550436,
umls-concept:C1705509,
umls-concept:C1710133
|
pubmed:issue |
10
|
pubmed:dateCreated |
2001-3-8
|
pubmed:abstractText |
The aim of this randomised trial was to evaluate the activity and toxicity of a biweekly regimen including 6S-leucovorin-modulated 5-fluorouracil (LFA-5-FU), combined with either irinotecan (CPT-11 + LFA 5-FU) or raltitrexed (Tomudex) (TOM + LFA-5-FU), in advanced colorectal cancer patients, and to make a preliminary comparison of both these experimental regimens with a biweekly administration of LFA-5-FU modulated by methotrexate (MTX + LFA-5-FU).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0923-7534
|
pubmed:author |
pubmed-author:AvalloneAA,
pubmed-author:BigliettoMM,
pubmed-author:CartenìGG,
pubmed-author:CasarettiRR,
pubmed-author:CatalanoGG,
pubmed-author:ComellaGG,
pubmed-author:ComellaPP,
pubmed-author:De LenaMM,
pubmed-author:De LuciaLL,
pubmed-author:De VitaFF,
pubmed-author:FarrisAA,
pubmed-author:IannielloG PGP,
pubmed-author:LayS ASA,
pubmed-author:LorussoVV,
pubmed-author:MancarellaSS
|
pubmed:issnType |
Print
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1323-33
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11106123-Adult,
pubmed-meshheading:11106123-Aged,
pubmed-meshheading:11106123-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:11106123-Camptothecin,
pubmed-meshheading:11106123-Colorectal Neoplasms,
pubmed-meshheading:11106123-Female,
pubmed-meshheading:11106123-Fluorouracil,
pubmed-meshheading:11106123-Humans,
pubmed-meshheading:11106123-Leucovorin,
pubmed-meshheading:11106123-Male,
pubmed-meshheading:11106123-Middle Aged,
pubmed-meshheading:11106123-Quality of Life,
pubmed-meshheading:11106123-Quinazolines,
pubmed-meshheading:11106123-Thiophenes,
pubmed-meshheading:11106123-Treatment Failure
|
pubmed:year |
2000
|
pubmed:articleTitle |
Biweekly irinotecan or raltitrexed plus 6S-leucovorin and bolus 5-fluorouracil in advanced colorectal carcinoma: a Southern Italy Cooperative Oncology Group phase II-III randomized trial.
|
pubmed:affiliation |
Division of Medical Oncology A. National Tumor Institute, Naples, Italy. pcomella@sirio-oncology.it
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II,
Clinical Trial, Phase III
|