Source:http://linkedlifedata.com/resource/pubmed/id/11105041
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2001-2-2
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pubmed:abstractText |
A technique for the simultaneous measurement of three vascular parameters: blood flow (Frho), blood volume (v(b)), and the capillary permeability-surface area product (PSrho) in breast tumors using dynamic contrast-enhanced magnetic resonance imaging (MRI) is presented. Features of the technique include measurement of precontrast tumor T(1), rapid temporal sampling, measurement of the arterial input function, and use of a distributed parameter tracer kinetic model. Parameter measurements are compared that were determined using two contrast agents of different molecular weights, gadolinium-diethylene triamine pentaacetic acid (Gd-DTPA; 0.6 kDa) and Gadomer-17 (17 kDa), in 18 spontaneous canine mammary tumors. Measurements of Frho and v(b) corresponded well with literature values, and the mean PSrho measured using Gd-DTPA was a factor of 15 higher than that measured using Gadomer-17. J. Magn. Reson. Imaging 2000;12:991-1003.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1053-1807
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
991-1003
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11105041-Animals,
pubmed-meshheading:11105041-Blood Flow Velocity,
pubmed-meshheading:11105041-Blood Volume,
pubmed-meshheading:11105041-Capillary Permeability,
pubmed-meshheading:11105041-Contrast Media,
pubmed-meshheading:11105041-Dog Diseases,
pubmed-meshheading:11105041-Dogs,
pubmed-meshheading:11105041-Female,
pubmed-meshheading:11105041-Gadolinium,
pubmed-meshheading:11105041-Gadolinium DTPA,
pubmed-meshheading:11105041-Magnetic Resonance Imaging,
pubmed-meshheading:11105041-Mammary Glands, Animal,
pubmed-meshheading:11105041-Mammary Neoplasms, Experimental,
pubmed-meshheading:11105041-Phantoms, Imaging,
pubmed-meshheading:11105041-Sensitivity and Specificity
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pubmed:year |
2000
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pubmed:articleTitle |
Simultaneous MRI measurement of blood flow, blood volume, and capillary permeability in mammary tumors using two different contrast agents.
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pubmed:affiliation |
Imaging Division, Lawson Health Research Institute, St. Joseph's Health Care, London, Ontario, Canada, N6A 4V2.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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