Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-12-20
pubmed:abstractText
Twenty-three years after introduction of coronary angioplasty (PTCA), the inhibition of restenosis formation continues to be the major challenge for the interventional cardiologist. About 35-50% of all patients undergoing PTCA develop a renarrowing of the intravascular lumen within the following six months. The use of specific systemic drug therapy as well as different angioplastic methods (rotablation, atherectomy, laser angioplasty) all failed to significantly reduce restenosis. Local drug delivery and local gene therapy have only shown to be effective in animal experiments. Restenosis can be reduced by the use of stents; however restenosis can also develop within the stents. The treatment of choice for severe in-stent restenosis may become radiotherapy, which seems to be a promising tool also for other forms of restenosis.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5860
pubmed:author
pubmed:issnType
Print
pubmed:volume
89 Suppl 7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-22
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:11098555-Angioplasty, Balloon, Coronary, pubmed-meshheading:11098555-Angioplasty, Balloon, Laser-Assisted, pubmed-meshheading:11098555-Anticholesteremic Agents, pubmed-meshheading:11098555-Atherectomy, pubmed-meshheading:11098555-Brachytherapy, pubmed-meshheading:11098555-Coronary Disease, pubmed-meshheading:11098555-Gene Therapy, pubmed-meshheading:11098555-Humans, pubmed-meshheading:11098555-Platelet Aggregation Inhibitors, pubmed-meshheading:11098555-Probucol, pubmed-meshheading:11098555-Prospective Studies, pubmed-meshheading:11098555-Randomized Controlled Trials as Topic, pubmed-meshheading:11098555-Recurrence, pubmed-meshheading:11098555-Risk Factors, pubmed-meshheading:11098555-Stents, pubmed-meshheading:11098555-Time Factors, pubmed-meshheading:11098555-Trapidil, pubmed-meshheading:11098555-Vasodilator Agents, pubmed-meshheading:11098555-Verapamil
pubmed:year
2000
pubmed:articleTitle
[New strategies in the treatment of restenosis].
pubmed:affiliation
Klinik für Innere Medizin/Kardiologie Herzzentrum Lahr/Baden, Lahr.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract