Source:http://linkedlifedata.com/resource/pubmed/id/11094867
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2000-12-22
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pubmed:abstractText |
Clinical success of pancreatic islet allograft (TX) for the therapy of diabetes mellitus is hampered by several pitfalls, primarily including the restricted availability of donor tissue and the immune- and/or non-immune-related TX's early loss, with the latter not necessarily being prevented by the host's general immunosuppression. Finally, adult islet beta-cells normally exhibit minimal proliferation capacity, which would not permit restoration of an eventually declining TX mass.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1081-5589
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
441-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11094867-Animals,
pubmed-meshheading:11094867-Coculture Techniques,
pubmed-meshheading:11094867-Diabetes Mellitus, Type 1,
pubmed-meshheading:11094867-Fetus,
pubmed-meshheading:11094867-Islets of Langerhans,
pubmed-meshheading:11094867-Islets of Langerhans Transplantation,
pubmed-meshheading:11094867-Male,
pubmed-meshheading:11094867-Rats,
pubmed-meshheading:11094867-Rats, Sprague-Dawley,
pubmed-meshheading:11094867-Sertoli Cells,
pubmed-meshheading:11094867-Transplantation, Homologous
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pubmed:year |
2000
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pubmed:articleTitle |
Sertoli cell-induced reversal of adult rat pancreatic islet beta-cells into fetal-like status: potential implications for islet transplantation in type I diabetes mellitus.
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pubmed:affiliation |
Department of Internal Medicine, University of Perugia, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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