Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2001-2-23
pubmed:abstractText
It is not known whether the amelioration of inflammation by corticosteroids is mediated through a direct effect on the T cells or by effects on other inflammatory cells and/or their products. To explore the mechanisms whereby corticosteroids exert their effects on T cell dependent inflammation we have used severe combined immunodeficiency (SCID) mice. These mice are largely devoid of functional T and B lymphocytes, hence being unable to raise delayed type hypersensitivity (DTH), but display intact antigen presenting capacity. The aim of this study was to analyse the target cell population participating in DTH and being affected by corticosteroid treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1023-3830
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
548-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Action of dexamethasone in the suppression of delayed-type hypersensitivity in reconstituted SCID mice.
pubmed:affiliation
Department of Rheumatology, University of Göteborg, Sweden. maria.taube@immuno.gu.se
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't