Source:http://linkedlifedata.com/resource/pubmed/id/11087498
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2001-1-12
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pubmed:abstractText |
Suppression of the furylfuramide-induced SOS response by 25 kinds monoterpenoids (hydrocarbons, alcohols, ketones, and aldehydes) with a p-menthane skeleton was studied. Suppression of the SOS-inducing activity by monoterpenoids was determined in the umu test using Salmonella typhimurium TA1535/pSK1002. The terpene alcohols, ketones, and aldehydes had potent suppressive effects, but the hydrocarbons did not. Especially, (+)-menthol, (+)-pulegone, piperitenone, and cuminaldehyde were shown to have the most potent suppressive effects, and the ID(50) (dose for 50% inhibition) was 0.52 micromol/mL.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0021-8561
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5440-3
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pubmed:meshHeading |
pubmed-meshheading:11087498-Alcohols,
pubmed-meshheading:11087498-Furylfuramide,
pubmed-meshheading:11087498-Menthol,
pubmed-meshheading:11087498-Molecular Structure,
pubmed-meshheading:11087498-Mutagenicity Tests,
pubmed-meshheading:11087498-SOS Response (Genetics),
pubmed-meshheading:11087498-Salmonella typhimurium,
pubmed-meshheading:11087498-Structure-Activity Relationship,
pubmed-meshheading:11087498-Terpenes
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pubmed:year |
2000
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pubmed:articleTitle |
Suppression of the furylfuramide-induced SOS response by monoterpenoids with a p-menthane skeleton using the Salmonella typhimurium TA1535/pSK1002 Umu test.
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pubmed:affiliation |
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka-shi, Osaka 577-8502, Japan. miyazawa@apch.kindai.ac.jp
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pubmed:publicationType |
Journal Article
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