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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2000-11-27
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pubmed:abstractText |
We recently discovered that short polymers of arginine efficiently translocate across the cytoplasmic membrane independent of the basic amino acid transporter. We evaluated the kinetics and biological effects of heptamers of L-arginine and D-arginine (L-R7 and D-R7, respectively) in vascular cells. We assessed the effects of these peptides on the NO synthesis pathway and vascular cell proliferation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
21
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2629-35
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11085967-Animals,
pubmed-meshheading:11085967-Biological Transport, Active,
pubmed-meshheading:11085967-Biotin,
pubmed-meshheading:11085967-Carotid Arteries,
pubmed-meshheading:11085967-Cell Division,
pubmed-meshheading:11085967-Cells, Cultured,
pubmed-meshheading:11085967-Dose-Response Relationship, Drug,
pubmed-meshheading:11085967-Graft Occlusion, Vascular,
pubmed-meshheading:11085967-Humans,
pubmed-meshheading:11085967-Hyperplasia,
pubmed-meshheading:11085967-Jugular Veins,
pubmed-meshheading:11085967-Male,
pubmed-meshheading:11085967-Muscle, Smooth, Vascular,
pubmed-meshheading:11085967-Nitrates,
pubmed-meshheading:11085967-Nitrites,
pubmed-meshheading:11085967-Oligopeptides,
pubmed-meshheading:11085967-Peptides,
pubmed-meshheading:11085967-Rabbits,
pubmed-meshheading:11085967-Temperature,
pubmed-meshheading:11085967-Transplantation, Autologous,
pubmed-meshheading:11085967-Tunica Intima
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pubmed:year |
2000
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pubmed:articleTitle |
Rapid and efficient vascular transport of arginine polymers inhibits myointimal hyperplasia.
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pubmed:affiliation |
Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305-5246, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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