Source:http://linkedlifedata.com/resource/pubmed/id/11085389
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
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| pubmed:dateCreated |
2000-12-1
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| pubmed:abstractText |
A small, isolated outbreak of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) due to dengue virus type 2 (DEN-2) was documented in Santiago de Cuba on the island of Cuba beginning in January 1997. There were 205 DHF/DSS cases, all in persons older than age 15 years. All but three had evidence of a prior dengue infection, with the only known opportunity being the islandwide dengue virus type 1 (DEN-1) epidemic of 1977-1979. Virtually complete clinical and laboratory surveillance of overt disease was achieved. From December 1997 to January 1998, a random, age-stratified serum sample was obtained from 1,151 persons in 40 residential clusters in Santiago. Sera were tested for DEN-1 and DEN-2 neutralizing antibodies. The prevalence of DEN-2 antibodies in children age 15 years and under, born after the 1981 DEN-2 epidemic, was taken as the 1997 DEN-2 infection rate. This was adjusted slightly to accommodate observed cases, resulting in an estimated infection rate of 4.3%. Dengue fever and DHF/DSS attack rates were calculated from estimated total primary and secondary DEN-2 infections. Only 3% of 13,116 primary infections were overt. The DHF/DSS attack rate for adults of all ages was 420 per 10,000 secondary DEN-2 infections.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
0002-9262
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:day |
1
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| pubmed:volume |
152
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
793-9; discussion 804
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:11085389-Adolescent,
pubmed-meshheading:11085389-Adult,
pubmed-meshheading:11085389-Age Distribution,
pubmed-meshheading:11085389-Aged,
pubmed-meshheading:11085389-Aged, 80 and over,
pubmed-meshheading:11085389-Antibodies, Viral,
pubmed-meshheading:11085389-Child,
pubmed-meshheading:11085389-Child, Preschool,
pubmed-meshheading:11085389-Cuba,
pubmed-meshheading:11085389-Dengue Hemorrhagic Fever,
pubmed-meshheading:11085389-Dengue Virus,
pubmed-meshheading:11085389-Disease Outbreaks,
pubmed-meshheading:11085389-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:11085389-Female,
pubmed-meshheading:11085389-Humans,
pubmed-meshheading:11085389-Infant,
pubmed-meshheading:11085389-Male,
pubmed-meshheading:11085389-Middle Aged,
pubmed-meshheading:11085389-Population Surveillance,
pubmed-meshheading:11085389-Seasons,
pubmed-meshheading:11085389-Seroepidemiologic Studies
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| pubmed:year |
2000
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| pubmed:articleTitle |
Epidemiologic studies on Dengue in Santiago de Cuba, 1997.
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| pubmed:affiliation |
Institute of Tropical Medicine Pedro Kouri, Havana, Cuba.
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| pubmed:publicationType |
Journal Article
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