rdf:type |
|
lifeskim:mentions |
umls-concept:C0007097,
umls-concept:C0007634,
umls-concept:C0019409,
umls-concept:C0042655,
umls-concept:C0086418,
umls-concept:C0205253,
umls-concept:C0332293,
umls-concept:C0439660,
umls-concept:C0677667,
umls-concept:C0950790,
umls-concept:C1883709
|
pubmed:issue |
4
|
pubmed:dateCreated |
2001-1-8
|
pubmed:abstractText |
Cellular heterogeneity in drug response has important clinical implications, and is believed to develop over many generations during clonal evolution in human tumors. The purpose of this study was to determine the level of heterogeneity exhibited by sister cells soon after their birth.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0196-4763
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
41
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
252-60
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:11084610-Aged,
pubmed-meshheading:11084610-Antimetabolites, Antineoplastic,
pubmed-meshheading:11084610-Cell Division,
pubmed-meshheading:11084610-Cell Lineage,
pubmed-meshheading:11084610-Clone Cells,
pubmed-meshheading:11084610-Humans,
pubmed-meshheading:11084610-Ileal Neoplasms,
pubmed-meshheading:11084610-Male,
pubmed-meshheading:11084610-Microscopy, Video,
pubmed-meshheading:11084610-Probability,
pubmed-meshheading:11084610-Quinazolines,
pubmed-meshheading:11084610-Thiophenes,
pubmed-meshheading:11084610-Tumor Cells, Cultured
|
pubmed:year |
2000
|
pubmed:articleTitle |
Time-lapse video reveals immediate heterogeneity and heritable damage among human ileocecal carcinoma HCT-8 cells treated with raltitrexed (ZD1694).
|
pubmed:affiliation |
Department of Pharmacology and Therapeutics and Grace Cancer Drug Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. Harry.Slocum@RoswellPark.org
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|