Source:http://linkedlifedata.com/resource/pubmed/id/11083069
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2001-2-27
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pubmed:abstractText |
A prospective study of 48 patients with pituitary adenomas, 19 adenomas causing Cushing's disease, 18 adenomas causing acromegaly, and 11 clinically hormone-inactive adenomas (inactive adenomas), was performed to study emotional disorders occurring before and after transsphenoidal microsurgery. Factors which led to an obvious delay in the diagnostic process were identified. - The tools utilised were an interview and repeated personality assessments. The personality assessments were begun preoperatively and continued for about half a year postoperatively. The interview data, including retrospective statements regarding somatic difficulties, was analysed. - The thesis of a uniform psychopathology due to the influence of elevated hormone levels, and a lack in patients' sensitivity towards their changed appearance in acromegaly could not be confirmed. A high variability of reported emotional problems was found. The most common psychopathological signs for Cushing's disease were excitability and depression, for acromegaly fatigue/loss of energy was the most frequent complaint. Six to eight months postoperatively, a majority of patients noticed an increase of physical well-being. In acromegaly, the time span between first consultation and diagnosis averaged 6.2 years, in Cushing's disease it was 4.3 years, and in inactive adenomas it was 3.9 years. Only a small part of the delay in diagnosis, less than two years, could be attributed to the patients' hesitation to consult a physician.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0947-7349
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
108
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
480-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11083069-Acromegaly,
pubmed-meshheading:11083069-Adenoma,
pubmed-meshheading:11083069-Adult,
pubmed-meshheading:11083069-Emotions,
pubmed-meshheading:11083069-Female,
pubmed-meshheading:11083069-Follow-Up Studies,
pubmed-meshheading:11083069-Humans,
pubmed-meshheading:11083069-Male,
pubmed-meshheading:11083069-Microsurgery,
pubmed-meshheading:11083069-Middle Aged,
pubmed-meshheading:11083069-Personality Inventory,
pubmed-meshheading:11083069-Pituitary Neoplasms
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pubmed:year |
2000
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pubmed:articleTitle |
Emotional disorders in patients with different types of pituitary adenomas and factors affecting the diagnostic process.
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pubmed:affiliation |
Clinic of Neurosurgery, University Hospital Eppendorf, Hamburg, Germany. flitsch@uke.uni-hamburg.de
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pubmed:publicationType |
Journal Article
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