Source:http://linkedlifedata.com/resource/pubmed/id/11079730
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2000-11-15
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pubmed:abstractText |
Alterations in the cell cycle regulatory p16INK4a/Cyclin D1/pRb pathway play a pivotal role in tumorigenesis. Knowledge of alterations in the tumor suppressor protein pRb and its negative regulator, p16CDKN2/MTS1/INK4a in esophageal squamous cell carcinoma (ESCC) from the Indian subcontinent is meager. To gain insight into the mechanisms underlying tumorigenesis and to search for diagnostic molecular markers for ESCC, we analyzed the expression of p16INK4a and pRb in ESCCs in the Indian population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0171-5216
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
655-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11079730-Adult,
pubmed-meshheading:11079730-Carcinoma, Squamous Cell,
pubmed-meshheading:11079730-Carrier Proteins,
pubmed-meshheading:11079730-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:11079730-Esophageal Neoplasms,
pubmed-meshheading:11079730-Female,
pubmed-meshheading:11079730-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11079730-Gene Silencing,
pubmed-meshheading:11079730-Genes, Tumor Suppressor,
pubmed-meshheading:11079730-Humans,
pubmed-meshheading:11079730-Immunohistochemistry,
pubmed-meshheading:11079730-Male,
pubmed-meshheading:11079730-Retinoblastoma Protein
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pubmed:year |
2000
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pubmed:articleTitle |
Frequent alterations in the expression of tumor suppressor genes p16INK4A and pRb in esophageal squamous cell carcinoma in the Indian population.
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pubmed:affiliation |
Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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