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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2000-11-20
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pubmed:abstractText |
Serotonin-1A (5-hydroxytryptamine-1A [5-HT1A]) receptors have been reported to play an important role in the pathophysiology of a variety of psychiatric and neurodegenerative disorders. Animal experiments have shown that 4-(2'-methoxyphenyl)-1-[2'-(N-2'-pyridinyl)-p-[18F]fluorobenzamido ]ethylpiperazine ([18F]MPPF) may be suitable for 5-HT1A receptor imaging in humans. The aim of this study was to determine if [18F]MPPF can be used for the quantitative analysis of 5-HT1A receptor densities in brain regions of healthy human volunteers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0161-5505
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1830-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11079490-Adult,
pubmed-meshheading:11079490-Aged,
pubmed-meshheading:11079490-Brain,
pubmed-meshheading:11079490-Cerebellum,
pubmed-meshheading:11079490-Female,
pubmed-meshheading:11079490-Frontal Lobe,
pubmed-meshheading:11079490-Humans,
pubmed-meshheading:11079490-Male,
pubmed-meshheading:11079490-Middle Aged,
pubmed-meshheading:11079490-Piperazines,
pubmed-meshheading:11079490-Pyridines,
pubmed-meshheading:11079490-Receptors, Serotonin,
pubmed-meshheading:11079490-Receptors, Serotonin, 5-HT1,
pubmed-meshheading:11079490-Temporal Lobe,
pubmed-meshheading:11079490-Tomography, Emission-Computed
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pubmed:year |
2000
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pubmed:articleTitle |
In vivo delineation of 5-HT1A receptors in human brain with [18F]MPPF.
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pubmed:affiliation |
PET Center, Groningen University Hospital, The Netherlands.
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pubmed:publicationType |
Journal Article
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