Source:http://linkedlifedata.com/resource/pubmed/id/11078201
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
21
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pubmed:dateCreated |
2001-2-7
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pubmed:abstractText |
In order to clarify the structural difference between active pinacidil-type potassium channel openers and a less active one, the tautomerisms of pinacidil derivatives 1-3 were investigated by NMR spectrometries. The predominant tautomer of the less active compound 3 was different from those of the active compounds 1 and 2.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2463-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11078201-Antihypertensive Agents,
pubmed-meshheading:11078201-Drug Design,
pubmed-meshheading:11078201-Humans,
pubmed-meshheading:11078201-Isomerism,
pubmed-meshheading:11078201-Magnetic Resonance Spectroscopy,
pubmed-meshheading:11078201-Molecular Structure,
pubmed-meshheading:11078201-Pinacidil,
pubmed-meshheading:11078201-Potassium Channels
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pubmed:year |
2000
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pubmed:articleTitle |
NMR analysis of tautomerisms of active pinacidil-type potassium channel openers and a less active one.
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pubmed:affiliation |
Chemistry, Group, R&D Laboratories, Nippon Organon K.K., Osaka, Japan. yoshiizumi.kazuya@organon.co.jp
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pubmed:publicationType |
Journal Article
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