Source:http://linkedlifedata.com/resource/pubmed/id/11077940
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2000-12-5
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pubmed:abstractText |
Lysozyme level was measured in the fluid and serum of 42 tuberculous (25 pleural, 11 ascites and 6 pericardial) and 29 non-tuberculous (5 malignant, 9 empyema thoracis, 10 transudative ascites and 5 pyopericardium) effusions. The mean fluid lysozyme level was significantly raised in tuberculous pleural, ascites, and pericardial effusions in comparison to malignant pleural (p <0.001), transudative ascites (p < 0.001), and pyopericardium (p < 0.02) cases, respectively. The mean fluid/serum lysozyme ratio did not differ significantly between tuberculous and their corresponding non-tuberculous effusions. The confirmed tuberculous pleural effusion patients had significantly higher mean fluid lysozyme level and fluid/serum lysozyme ratio when compared with clinical cases (p < 0.05). The cut-off fluid lysozyme level of > or = 50/UI(-1) and fluid/serum lysozyme ratio of > or = 1.1 were considered for the diagnosis of tuberculous effusions; the sensitivity and specificity of fluid lysozyme and fluid/serum lysozyme ratios were 100, 100 per cent, and 97.6, 33.3 per cent, respectively, on excluding the patients with purulent effusions. A significant correlation was observed between the fluid and serum lysozyme levels in tuberculous effusions (r = 0.39,p < 0.01). Thus, fluid lysozyme was found to be a better and reliable test than fluid/serum lysozyme ratio for the diagnosis of tuberculous effusions in children.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0142-6338
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
296-300
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11077940-Adolescent,
pubmed-meshheading:11077940-Ascitic Fluid,
pubmed-meshheading:11077940-Biological Markers,
pubmed-meshheading:11077940-Child,
pubmed-meshheading:11077940-Child, Preschool,
pubmed-meshheading:11077940-Female,
pubmed-meshheading:11077940-Humans,
pubmed-meshheading:11077940-Infant,
pubmed-meshheading:11077940-Male,
pubmed-meshheading:11077940-Muramidase,
pubmed-meshheading:11077940-Pericardial Effusion,
pubmed-meshheading:11077940-Pleural Effusion,
pubmed-meshheading:11077940-Reference Values,
pubmed-meshheading:11077940-Regression Analysis,
pubmed-meshheading:11077940-Sensitivity and Specificity,
pubmed-meshheading:11077940-Tuberculosis
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pubmed:year |
2000
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pubmed:articleTitle |
Lysozyme levels for the diagnosis of tuberculous effusions in children.
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pubmed:affiliation |
Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial
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