rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-11-27
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pubmed:abstractText |
Previously it was demonstrated that in prostate tumors, angiogenesis measured as microvessel density (MVD) is associated with tumor stage as well as WHO grade and is an independent predictor of clinical outcome. Vascular endothelial growth factor (VEGF) is a major inducer of angiogenesis. There is some evidence that P53 mutations cause overexpression of VEGF. We studied VEGF expression, p53 overexpression, and P53 mutations in prostate cancer (PCA) to investigate the role of VEGF as an angiogenic marker and the possible deregulation of VEGF as a result of P53 mutations in PCA.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0270-4137
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
216-24
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11074523-Adult,
pubmed-meshheading:11074523-Endothelial Growth Factors,
pubmed-meshheading:11074523-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:11074523-Genes, p53,
pubmed-meshheading:11074523-Humans,
pubmed-meshheading:11074523-Lymphokines,
pubmed-meshheading:11074523-Male,
pubmed-meshheading:11074523-Neoplasm Staging,
pubmed-meshheading:11074523-Neovascularization, Pathologic,
pubmed-meshheading:11074523-Prognosis,
pubmed-meshheading:11074523-Prostatic Neoplasms,
pubmed-meshheading:11074523-Vascular Endothelial Growth Factor A,
pubmed-meshheading:11074523-Vascular Endothelial Growth Factors
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pubmed:year |
2000
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pubmed:articleTitle |
Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer.
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pubmed:affiliation |
Department of Urology, University of Innsbruck, Austria. Dagmar.Strohmeyer@uibk.ac.at
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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