Linked Life Data

11072764

Source:http://linkedlifedata.com/resource/pubmed/id/11072764

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-4-5
pubmed:abstractText
Anticholinergics are widely used to treat extrapyramidal motor symptoms caused by neuroleptics or other drugs with antidopaminergic (dopamine D2) effects. In the medical literature, occasional reports are concerned with the abuse of centrally acting anticholinergic compounds. These drugs may be abused because of their stimulant effects, mostly by patients on neuroleptic treatment. Their supposed "euphoric" effect when too quickly parenterally administered (only after previous treatment with neuroleptics) seems to consist in the abolition of neuroleptic-induced anhedonia. In a few patients, excessive use of anticholinergics persists in the face of detrimental effects and is, therefore, properly termed "abuse". More commonly, however, patients with schizophrenia take more than the recommended dose of anticholinergics in an attempt to treat the adverse effects of neuroleptics. The abuse of anticholinergics in addicts who are not using neuroleptics is low.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0176-3679
pubmed:author
pubmed:issnType
Print
pubmed:volume
33 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-6
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Abuse potential of anticholinergics.
pubmed:affiliation
BKH Taufkirchen, Germany.
pubmed:publicationType
Journal Article, Review