Linked Life Data

11072511

Source:http://linkedlifedata.com/resource/pubmed/id/11072511

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
43
pubmed:dateCreated
2000-11-29
pubmed:abstractText
The antiepileptic drug vigabatrin causes an asymptotic concentric contraction of the visual field in 30 to 40% of the patients. The visual field loss seems to be correlated with the cumulative dose of vigabatrin and is not reversible. The cause of this field loss is located in the inner retina (the horizontal and/or amacrine cells). The exact mechanism is still unknown. Though abnormalities in electrophysiology and colour vision are found, regular visual field examination remains the cornerstone in detecting visual field loss. A careful judgement has to be made in individual patients before starting or continuing vigabatrin medication.
pubmed:language
dut
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0028-2162
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
144
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2066-9
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
[Vigabatrin: balancing effectiveness vs. (irreversible) visual field loss as a side effect].
pubmed:affiliation
Academisch Ziekenhuis, afd. Oogheelkunde, Groningen. p.l.l.j.hardus@ohk.azg.nl
pubmed:publicationType
Journal Article, English Abstract, Review