Source:http://linkedlifedata.com/resource/pubmed/id/11072254
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2000-11-14
|
| pubmed:abstractText |
The association between cigarette smoking and lung cancer risk in women was investigated within the framework of a case-control study in 9 centres from 6 European countries. Cases were 1,556 women up to 75 years of age with histologically confirmed primary lung cancer; 2, 450 controls with age distribution similar to cases were selected. The predominant cell type was adenocarcinoma (33.5%), with similar proportions for squamous-cell type (26.4%) and small-cell carcinoma (22.3%). Overall, smoking cigarettes at any time was associated with a 5-fold increase in lung cancer risk (odds ratio 5.21, 95% confidence interval 4.49-6.04); corresponding figures for current smoking habits were 8.94, 7.54-10.6. The association showed a dose-response relationship with duration of the habit and daily and cumulative lifetime smoking. A significant excess risk of 70% was associated with every 10 pack-years smoked. After 10 years of smoking cessation, the relative risk decreased to 20% compared to current smokers. The following characteristics were associated with a higher relative risk: inhalation of smoke, smoking non-filter cigarettes, smoking dark-type cigarettes and starting at young age. The association was observed for all major histological types, being the strongest for small-cell type carcinoma, followed by squamous-cell type and the lowest for adenocarcinoma. The proportion of lung-cancer cases in the population attributable to cigarette smoking ranged from 14% to 85%. We concluded that women share most features of the association between cigarette smoking and lung cancer observed in men.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0020-7136
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| pubmed:author |
pubmed-author:AgudoAA,
pubmed-author:AhrensWW,
pubmed-author:BenhamouEE,
pubmed-author:BenhamouSS,
pubmed-author:BoffettaPP,
pubmed-author:DarbyS CSC,
pubmed-author:ForastiereFF,
pubmed-author:FortesCC,
pubmed-author:GaborieauVV,
pubmed-author:GonzálezC ACA,
pubmed-author:JöckelK HKH,
pubmed-author:KreuzerMM,
pubmed-author:MerletteBB,
pubmed-author:PohlabelnHH,
pubmed-author:RichiardiLL,
pubmed-author:SimonatoLL,
pubmed-author:WhitleyEE,
pubmed-author:WichmannH EHE,
pubmed-author:ZambonPP
|
| pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
|
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
88
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
820-7
|
| pubmed:dateRevised |
2007-7-24
|
| pubmed:meshHeading |
pubmed-meshheading:11072254-Adult,
pubmed-meshheading:11072254-Aged,
pubmed-meshheading:11072254-Case-Control Studies,
pubmed-meshheading:11072254-Europe,
pubmed-meshheading:11072254-Female,
pubmed-meshheading:11072254-Humans,
pubmed-meshheading:11072254-Lung Neoplasms,
pubmed-meshheading:11072254-Middle Aged,
pubmed-meshheading:11072254-Odds Ratio,
pubmed-meshheading:11072254-Risk Factors,
pubmed-meshheading:11072254-Smoking,
pubmed-meshheading:11072254-Women's Health
|
| pubmed:year |
2000
|
| pubmed:articleTitle |
Lung cancer and cigarette smoking in women: a multicenter case-control study in Europe.
|
| pubmed:affiliation |
Catalan Institute of Oncology, L'Hospitalet, Barcelona, Spain. a.agudo@ico.scs.es
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|