Source:http://linkedlifedata.com/resource/pubmed/id/11071568
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2001-2-5
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pubmed:abstractText |
The human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus, is a gamma herpesvirus associated with AIDS-related body cavity-based lymphomas (BCBL), also called primary effusion lymphomas (PEL). These are a rare form of non-Hodgkin lymphomas in which HHV-8 is present, often associated with Epstein-Barr virus (EBV) infection. HHV-8 is also present in a latent state or in a state of low-level persistence in different primary effusion lymphoma-derived cell lines, such BCBL-1 cells, that lack EBV infection. This cell line was induced to produce mature virions by treatment with 12-O-tetradecanoyl phorbol-13-acetate (TPA) and the characteristic ultrastructural features of HHV-8 lytic replication were identified and compared to those of the other members of Herpesviridae family.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0191-3123
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-10
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pubmed:dateRevised |
2009-6-26
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pubmed:meshHeading |
pubmed-meshheading:11071568-Apoptosis,
pubmed-meshheading:11071568-Butyrates,
pubmed-meshheading:11071568-Herpesvirus 8, Human,
pubmed-meshheading:11071568-Humans,
pubmed-meshheading:11071568-Lymphoma, AIDS-Related,
pubmed-meshheading:11071568-Microscopy, Electron,
pubmed-meshheading:11071568-Organelles,
pubmed-meshheading:11071568-Pleural Effusion, Malignant,
pubmed-meshheading:11071568-Sarcoma, Kaposi,
pubmed-meshheading:11071568-Species Specificity,
pubmed-meshheading:11071568-Tetradecanoylphorbol Acetate,
pubmed-meshheading:11071568-Tumor Cells, Cultured,
pubmed-meshheading:11071568-Virus Replication
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pubmed:articleTitle |
Lytic growth of human herpesvirus 8: morphological aspects.
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pubmed:affiliation |
Laboratory of Ultrastructure, Istituto Superiore di Sanità, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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