Source:http://linkedlifedata.com/resource/pubmed/id/11069236
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2000-12-26
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| pubmed:abstractText |
The effects of human immunodeficiency virus (HIV) type 1 on the placenta and the role of the placenta in mother-to-child HIV-1 transmission are not well understood. Placentas from 78 HIV-infected and 158 HIV-uninfected women were examined as part of a prospective perinatal HIV transmission study in Bangkok. HIV-infected women were more likely than HIV-uninfected women to have chorioamnionitis (odds ratio [OR], 2.1; P=.03), placental membrane inflammation (PMI; OR, 2. 7; P=.02), and deciduitis (OR, 2.3; P=.03) and less likely to have villitis (OR, 0.3; P=.02). However, among HIV-infected women, fewer women who transmitted infection to their child had chorioamnionitis (relative risk [RR], 0.2; P=.03), funisitis (RR, 0.4; P=.1), or PMI (RR undefined; P=.03). These findings suggest that, in this population, HIV-infected women are at increased risk for placental membrane inflammatory lesions, but that placental inflammatory lesions are not associated with increased perinatal HIV transmission.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0022-1899
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
182
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1652-7
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| pubmed:dateRevised |
2008-11-21
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| pubmed:meshHeading |
pubmed-meshheading:11069236-Adolescent,
pubmed-meshheading:11069236-Adult,
pubmed-meshheading:11069236-Chorioamnionitis,
pubmed-meshheading:11069236-Chorionic Villi,
pubmed-meshheading:11069236-Cohort Studies,
pubmed-meshheading:11069236-Decidua,
pubmed-meshheading:11069236-Female,
pubmed-meshheading:11069236-HIV Infections,
pubmed-meshheading:11069236-HIV-1,
pubmed-meshheading:11069236-Humans,
pubmed-meshheading:11069236-Infant,
pubmed-meshheading:11069236-Infant, Newborn,
pubmed-meshheading:11069236-Infectious Disease Transmission, Vertical,
pubmed-meshheading:11069236-Placenta,
pubmed-meshheading:11069236-Pregnancy,
pubmed-meshheading:11069236-Pregnancy Complications, Infectious,
pubmed-meshheading:11069236-Prospective Studies,
pubmed-meshheading:11069236-Risk Factors,
pubmed-meshheading:11069236-Thailand,
pubmed-meshheading:11069236-Umbilical Cord
|
| pubmed:year |
2000
|
| pubmed:articleTitle |
Placental abnormalities associated with human immunodeficiency virus type 1 infection and perinatal transmission in Bangkok, Thailand.
|
| pubmed:affiliation |
Departments of Pathology and Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|