Source:http://linkedlifedata.com/resource/pubmed/id/11063801
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-12-4
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pubmed:abstractText |
We present a cytogenetic and fluorescence in situ hybridization (FISH) study, using centromeric probes for chromosomes 3, 7, 11, and 18, TP53 gene (17p13), and RB-1 locus (13q14) DNA probes, in four cases of plasma cell leukemia (PCL). Among the four cases, three presented monosomy of the RB-1 locus and one monoallelic deletion of the TP53 gene. The present report shows the usefulness of the FISH technique to detect abnormalities not previously observed by conventional cytogenetics.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0165-4608
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11063801-Adult,
pubmed-meshheading:11063801-Aged,
pubmed-meshheading:11063801-Aged, 80 and over,
pubmed-meshheading:11063801-DNA, Satellite,
pubmed-meshheading:11063801-DNA Probes,
pubmed-meshheading:11063801-Female,
pubmed-meshheading:11063801-Genes, Retinoblastoma,
pubmed-meshheading:11063801-Genes, p53,
pubmed-meshheading:11063801-Humans,
pubmed-meshheading:11063801-In Situ Hybridization, Fluorescence,
pubmed-meshheading:11063801-Leukemia, Plasma Cell,
pubmed-meshheading:11063801-Male
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pubmed:year |
2000
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pubmed:articleTitle |
Cytogenetic and fluorescence in situ hybridization studies in four cases of plasma cell leukemia.
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pubmed:affiliation |
Laboratori de Citologia Hematològica/Laboratori de Referència de Catalunya, Unitat d'Hematologia, Hospital del Mar, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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