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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-3-22
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pubmed:abstractText |
Depletion of nitric oxide may play a role in the development of vasospasm after aneurysmal subarachnoid hemorrhage. Replenishment of nitric oxide might be a useful treatment for vasospasm. Using rats, we performed intracisternal injections of replication-defective adenovirus containing the endothelial nitric oxide synthase (eNOS) gene and determined the localization of and effect on cerebral blood flow of transgene expression.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0148-396X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1206-14; discussion 1214-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11063115-Animals,
pubmed-meshheading:11063115-Brain,
pubmed-meshheading:11063115-Cerebrovascular Circulation,
pubmed-meshheading:11063115-DNA Primers,
pubmed-meshheading:11063115-Gene Transfer Techniques,
pubmed-meshheading:11063115-Genes, Viral,
pubmed-meshheading:11063115-Lac Operon,
pubmed-meshheading:11063115-Laser-Doppler Flowmetry,
pubmed-meshheading:11063115-Mastadenovirus,
pubmed-meshheading:11063115-Nitric Oxide Synthase,
pubmed-meshheading:11063115-RNA, Messenger,
pubmed-meshheading:11063115-RNA, Viral,
pubmed-meshheading:11063115-Rats,
pubmed-meshheading:11063115-Rats, Sprague-Dawley,
pubmed-meshheading:11063115-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11063115-Subarachnoid Space,
pubmed-meshheading:11063115-Time Factors,
pubmed-meshheading:11063115-Transgenes,
pubmed-meshheading:11063115-beta-Galactosidase
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pubmed:year |
2000
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pubmed:articleTitle |
Adenoviral gene transfer of nitric oxide synthase increases cerebral blood flow in rats.
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pubmed:affiliation |
Section of Neurosurgery, Pritzker School of Medicine, University of Chicago Medical Center, Illinois 60637, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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