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11062729
Source:
http://linkedlifedata.com/resource/pubmed/id/11062729
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0007586
,
umls-concept:C0007634
,
umls-concept:C0015133
,
umls-concept:C0023473
,
umls-concept:C0439828
,
umls-concept:C1280500
,
umls-concept:C1552913
pubmed:issue
5A
pubmed:dateCreated
2000-12-11
pubmed:abstractText
Etoposide, a DNA-topoisomerase II inhibitor, is used for a broad spectrum of cancers with various therapeutic strategies. But the molecular mechanisms of its concentration-dependent effects are not clearly defined.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/8102988
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, Phytogenic
,
http://linkedlifedata.com/resource/pubmed/chemical/CCNB1 protein, human
,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin B
,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin B1
,
http://linkedlifedata.com/resource/pubmed/chemical/Etoposide
,
http://linkedlifedata.com/resource/pubmed/chemical/Nucleic Acid Synthesis Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinases
,
http://linkedlifedata.com/resource/pubmed/chemical/Topoisomerase II Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/histone H1 kinase
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed-author:FukumaKK
,
pubmed-author:Horiguchi-YamadaJJ
,
pubmed-author:IwaseSS
,
pubmed-author:OhnoTT
,
pubmed-author:YamadaHH
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3105-10
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:11062729-Antineoplastic Agents, Phytogenic
,
pubmed-meshheading:11062729-Cell Cycle
,
pubmed-meshheading:11062729-Cyclin B
,
pubmed-meshheading:11062729-Cyclin B1
,
pubmed-meshheading:11062729-Dose-Response Relationship, Drug
,
pubmed-meshheading:11062729-Etoposide
,
pubmed-meshheading:11062729-Gene Expression Regulation
,
pubmed-meshheading:11062729-Humans
,
pubmed-meshheading:11062729-K562 Cells
,
pubmed-meshheading:11062729-Leukemia, Myelogenous, Chronic, BCR-ABL Positive
,
pubmed-meshheading:11062729-Nucleic Acid Synthesis Inhibitors
,
pubmed-meshheading:11062729-Protein Kinases
,
pubmed-meshheading:11062729-Topoisomerase II Inhibitors
pubmed:articleTitle
Concentration-dependent variable effects of etoposide on the cell cycle of CML cells.
pubmed:affiliation
Department of Oncology, Jikei University School of Medicine, Tokyo, Japan.
pubmed:publicationType
Journal Article
,
Research Support, Non-U.S. Gov't