| pubmed-article:1106193 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1106193 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:1106193 | lifeskim:mentions | umls-concept:C0005767 | lld:lifeskim |
| pubmed-article:1106193 | lifeskim:mentions | umls-concept:C0024204 | lld:lifeskim |
| pubmed-article:1106193 | lifeskim:mentions | umls-concept:C0079772 | lld:lifeskim |
| pubmed-article:1106193 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:1106193 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:1106193 | pubmed:dateCreated | 1976-2-9 | lld:pubmed |
| pubmed-article:1106193 | pubmed:abstractText | B and T cell populations were studied in blood and neoplastic tissues from 64 untreated and 23 treated patients with non-Hodgkin's lymphoma. This study was undertaken primarily to evaluate the relation of B and T cell markers in various lymphomas to the currently accepted morphologic classifications and to determine the utility of various tissues in defining the cell of origin of a lymphoma. When histologically involved blood, bone marrow, lymph nodes or body fluids were studied, a B or T cell origin of the lymphoma was identified in 26 of 28 (68 per cent) patients. A B cell origin was found in 17 adults classified as having nodular (N) or diffuse (D) poorly differentiated lymphocytic lymphoma (PDLL). One lymphoma of T cell origin was observed in an adult with poorly differentiated lymphocytic lymphoma-diffuse (PDLL-D). In contrast, all cases of PDLL-D in children were T cell in origin. The origin of American Burkitt's (stem cell) lymphoma in two children was the B cell. When histologically involved blood was studied, a B or T cell origin was demonstrated in 10 of 21 (48 percent) adults. Evidence of a monoclonal proliferation of B lymphocytes in the blood was found two adults with more than 7 per cent lymphoma cells in Wright-Giemsa stained blood smears. When neoplastic lymph nodes were studied, the diagnosis of a B cell lymphoma was made in 8 of 12 (67 per cent) adults. Study of surface markers on malignant cells in cerebrospinal or serosal fluids frequently revealed a B or T cell origin of the lymphoma. B and T lymphocyte numbers in the blood did not correlate with immunoglobulin or skin test abnormalities. Abnormalities in circulating B or T cell percentages at diagnosis were a poor prognostic sign in patients with PDLL-D. | lld:pubmed |
| pubmed-article:1106193 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1106193 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1106193 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:1106193 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1106193 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1106193 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1106193 | pubmed:issn | 0002-9343 | lld:pubmed |
| pubmed-article:1106193 | pubmed:author | pubmed-author:KerseyJ HJH | lld:pubmed |
| pubmed-article:1106193 | pubmed:author | pubmed-author:BrunningR DRD | lld:pubmed |
| pubmed-article:1106193 | pubmed:author | pubmed-author:BloomfieldC... | lld:pubmed |
| pubmed-article:1106193 | pubmed:author | pubmed-author:CocciaP FPF | lld:pubmed |
| pubmed-article:1106193 | pubmed:author | pubmed-author:Gajl-Peczalsk... | lld:pubmed |
| pubmed-article:1106193 | pubmed:author | pubmed-author:SosinHH | lld:pubmed |
| pubmed-article:1106193 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1106193 | pubmed:volume | 59 | lld:pubmed |
| pubmed-article:1106193 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1106193 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1106193 | pubmed:pagination | 674-85 | lld:pubmed |
| pubmed-article:1106193 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:1106193 | pubmed:meshHeading | pubmed-meshheading:1106193-... | lld:pubmed |
| pubmed-article:1106193 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:1106193 | pubmed:articleTitle | B and T cell lymphomas. Analysis of blood and lymph nodes in 87 patients. | lld:pubmed |
| pubmed-article:1106193 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1106193 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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