Linked Life Data

1105792

Source:http://linkedlifedata.com/resource/pubmed/id/1105792

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-2-9
pubmed:abstractText
Since erythropoiesis is regulated at a number of steps, it seems likely that multiple genetically determined defects could result in polycythemia in families. These defects might be recognized by distinct patterns of marrow regulation--physiologic studies relating ESF production, oxygen transport, and red cell production in affected individuals. Defects in renal or extrarenal mechanisms of ESF production and release, oxygen sensing by the kidney, and in receptor site number or function on target cells within the marrow should be characterized by distinctive patterns of ESF production at rest and in response to altered oxygen supply. Continued study should allow the dissection of levels of regulation under genetic control and lead to a better understanding of the physiology of red cell production in normal man.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0037-1963
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
383-96
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Familial polycythemia.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review