Linked Life Data

11055120

Source:http://linkedlifedata.com/resource/pubmed/id/11055120

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2000-11-13
pubmed:abstractText
Hormone sensitive lipase (HSL) is a key enzyme in fat metabolism. The polymorphism of the pig HSL gene is studied in this paper. The SSCP (Single Strand Conformational Polymorphism) is found in the HSL gene Exon 8. It shows three genotypes (MM, MN, NN). Fat-type pig breeds of Meishan and Tongcheng pigs have more allele M, with frequencies of 0.690 M and 0.740 M, respectively; however, lean-type pig breeds of Landrace and the Large White pigs have more allele N, with frequencies of 0.847 N and 0.845 N, respectively. PCR fragments representing HSL genotypes MM and NN are sequenced. Two A-->G transitions are detected, and it resulted in corresponding changes of amino acid (Asn-->Asp and Glu-->Gly) in the HSL protein, respectively. The HSL gene can be considered as a candidate gene for fatness in pigs.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0379-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
686-90
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
[Polymorphism of porcine hormone sensitive lipase gene and sequencing the partial DNA fragments].
pubmed:affiliation
College of Animal Science, Huazhong Agricultural University, Wuhan, China.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't