Source:http://linkedlifedata.com/resource/pubmed/id/11052549
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
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| pubmed:dateCreated |
2000-11-13
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| pubmed:abstractText |
The authors assessed risk factors for cervical intraepithelial neoplasia (CIN) among southwestern American Indian women using case-control methods. Cases were New Mexico American Indian women with biopsy-proven grade I (n = 190), grade II (n = 70), or grade III (n = 42) cervical lesions diagnosed between November 1994 and October 1997. Controls were American Indian women from the same Indian Health Service clinics with normal cervical epithelium (n = 326). All subjects underwent interviews and laboratory evaluations. Interviews focused on history of sexually transmitted diseases, sexual behavior, and cigarette smoking. Laboratory assays included polymerase chain reaction-based tests for cervical human papillomavirus infection, tests for gonorrhea and chlamydia, wet mounts, and serologic assays for antibodies to Treponema pallidum, herpes simplex virus, and hepatitis B and C viruses. In multiple logistic regression analysis, the strongest risk factors for CIN II/III among American Indian women were human papillomavirus type 16 infection (adjusted odds ratio (OR) = 7.6; 95% confidence interval (CI): 2.4, 23.2), any human papillomavirus infection (OR = 5.8; 95% CI: 3.3, 10.0), low income (OR = 3.3; 95% CI: 1.7, 6.2), and history of any sexually transmitted disease (OR = 2.0; 95% CI: 1.1, 3.5). Unlike previous research, this study found no strong associations between CIN and sexual activity or cigarette smoking.
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| pubmed:grant | |
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Oct
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| pubmed:issn |
0002-9262
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:day |
15
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| pubmed:volume |
152
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
716-26
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| pubmed:dateRevised |
2007-11-14
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| pubmed:meshHeading |
pubmed-meshheading:11052549-Adolescent,
pubmed-meshheading:11052549-Adult,
pubmed-meshheading:11052549-Case-Control Studies,
pubmed-meshheading:11052549-Cervical Intraepithelial Neoplasia,
pubmed-meshheading:11052549-Female,
pubmed-meshheading:11052549-Humans,
pubmed-meshheading:11052549-Indians, North American,
pubmed-meshheading:11052549-Logistic Models,
pubmed-meshheading:11052549-Marital Status,
pubmed-meshheading:11052549-Middle Aged,
pubmed-meshheading:11052549-New Mexico,
pubmed-meshheading:11052549-Papillomaviridae,
pubmed-meshheading:11052549-Papillomavirus Infections,
pubmed-meshheading:11052549-Polymerase Chain Reaction,
pubmed-meshheading:11052549-Risk Factors,
pubmed-meshheading:11052549-Severity of Illness Index,
pubmed-meshheading:11052549-Sexual Behavior,
pubmed-meshheading:11052549-Sexually Transmitted Diseases,
pubmed-meshheading:11052549-Smoking,
pubmed-meshheading:11052549-Tumor Virus Infections
|
| pubmed:year |
2000
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| pubmed:articleTitle |
Risk factors for cervical intraepithelial neoplasia in southwestern American Indian women.
|
| pubmed:affiliation |
Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, USA. mschiff@u.washington.edu
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|