Linked Life Data

11052506

Source:http://linkedlifedata.com/resource/pubmed/id/11052506

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-10-27
pubmed:abstractText
Many biomechanical studies are performed on dense connective tissues in the laboratory over a substantial time period; however, the effect of the in vitro testing environment on the cyclic load-relaxation behaviour of these structures is not well established. This study evaluated the effect of long duration of testing on ligament viscoelastic behaviour, using the rabbit femur-medial collateral ligament-tibia complex as a model. Dissected rabbit knee joints were mounted on a materials testing machine, and isolated ligament complexes were cycled at a frequency of one cycle/min to a fixed displacement of 0.7 mm for an 18-hour period. After an initial period of exponential load relaxation, the cyclic peak loads slowly decreased over the 18-hour period. The average decrease in the cyclic peak load between 0.5 and 18.0 hours was 0.26% (of the original peak load) per hour (r2 = 0.934), or a total of 8.6+/-4.6% over this period (p < 0.0001). Thus, low-load testing of dense connective tissues in the laboratory over extended periods significantly alters their biomechanical behaviour, and these changes should be considered in long-term laboratory-based studies of dense connective tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0736-0266
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
678-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Effect of in vitro testing over extended periods on the low-load mechanical behaviour of dense connective tissues.
pubmed:affiliation
Bioengineering Laboratory, Hand and Upper Limb Centre, Lawson Research Institute, St. Joseph's Health Centre, London, Ontario, Canada. gking@julian.uwo.ca
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't