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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2001-1-29
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pubmed:abstractText |
Whether fibromatoses are neoplastic or reactive lesions has long been controversial and the relationship, if any, between the superficial and deep forms (desmoid tumors) are poorly understood. Clinical, pathologic, and cytogenetic data of 78 cases of fibromatosis were analyzed and correlated with each other. The results demonstrate that clonal chromosome aberrations are a common feature of this entity, being present in 46% of desmoid tumors, although less frequent in the superficial types (10%). In the deep-seated extra-abdominal fibromatoses, trisomies 8 and 20 and loss of 5q material were the only recurrent features. No correlation between +8 and local recurrence was found. Our findings provide additional evidence for the neoplastic nature of fibromatoses.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0893-3952
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pubmed:author |
pubmed-author:Dal CinPP,
pubmed-author:De WeverII,
pubmed-author:FletcherC DCD,
pubmed-author:MandahlNN,
pubmed-author:MertensFF,
pubmed-author:MitelmanFF,
pubmed-author:RosaiJJ,
pubmed-author:RydholmAA,
pubmed-author:SemelJ DJD,
pubmed-author:TalliniGG,
pubmed-author:Van Den BergheHH,
pubmed-author:VanniRR,
pubmed-author:WillénHH
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1080-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11048801-Adult,
pubmed-meshheading:11048801-Aged,
pubmed-meshheading:11048801-Aged, 80 and over,
pubmed-meshheading:11048801-Child,
pubmed-meshheading:11048801-Chromosome Aberrations,
pubmed-meshheading:11048801-Chromosomes, Human, Pair 20,
pubmed-meshheading:11048801-Chromosomes, Human, Pair 8,
pubmed-meshheading:11048801-Clone Cells,
pubmed-meshheading:11048801-Female,
pubmed-meshheading:11048801-Fibroma,
pubmed-meshheading:11048801-Fibromatosis, Aggressive,
pubmed-meshheading:11048801-Humans,
pubmed-meshheading:11048801-Karyotyping,
pubmed-meshheading:11048801-Male,
pubmed-meshheading:11048801-Middle Aged,
pubmed-meshheading:11048801-Multicenter Studies as Topic,
pubmed-meshheading:11048801-Single-Blind Method,
pubmed-meshheading:11048801-Soft Tissue Neoplasms,
pubmed-meshheading:11048801-Trisomy
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pubmed:year |
2000
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pubmed:articleTitle |
Cytogenetic, clinical, and morphologic correlations in 78 cases of fibromatosis: a report from the CHAMP Study Group. CHromosomes And Morphology.
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pubmed:affiliation |
Department of Surgical Oncology, University of Leuven, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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