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rdf:type |
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lifeskim:mentions |
umls-concept:C0003069,
umls-concept:C0009498,
umls-concept:C0023884,
umls-concept:C0024501,
umls-concept:C0039005,
umls-concept:C0086418,
umls-concept:C0108793,
umls-concept:C0237798,
umls-concept:C0311400,
umls-concept:C0427579,
umls-concept:C0439228,
umls-concept:C0441509,
umls-concept:C0522537,
umls-concept:C0542341,
umls-concept:C0547043,
umls-concept:C0721534,
umls-concept:C1704735
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pubmed:issue |
7
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pubmed:dateCreated |
2000-10-24
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pubmed:abstractText |
It is not known whether the pig liver is capable of functioning efficiently when transplanted into a primate, neither is there experience in transplanting a liver from a transgenic pigs expressing the human complement regulator human complement regulator decay accelerating factor (h-DAF) into a baboon. The objective of this study was to determine whether the porcine liver would support the metabolic functions of non-human primates and to establish the effect of hDAF expression in the prevention of hyperacute rejection of porcine livers transplanted into primates.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0041-1337
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pubmed:author |
pubmed-author:AcostaFF,
pubmed-author:AsensiHH,
pubmed-author:BuoenL CLC,
pubmed-author:CabezueloJJ,
pubmed-author:CalneR YRY,
pubmed-author:CayuelaM GMG,
pubmed-author:ChavezRR,
pubmed-author:CozziEE,
pubmed-author:FuenteTT,
pubmed-author:GagoM RMR,
pubmed-author:HernandezQQ,
pubmed-author:LobaMM,
pubmed-author:MajadoMM,
pubmed-author:MarinFF,
pubmed-author:MinguelaAA,
pubmed-author:MuñozAA,
pubmed-author:MunitizVV,
pubmed-author:NavarroFF,
pubmed-author:PalencianoC GCG,
pubmed-author:ParrillaPP,
pubmed-author:Pino-ChavezGG,
pubmed-author:RamirezPP,
pubmed-author:RoblesRR,
pubmed-author:RodriguezJ MJM,
pubmed-author:RubioAA,
pubmed-author:SansanoTT,
pubmed-author:SeguraBB,
pubmed-author:VizcainoA SAS,
pubmed-author:WhiteD JDJ,
pubmed-author:YelamosJJ
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
989-98
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11045632-Acute Disease,
pubmed-meshheading:11045632-Animals,
pubmed-meshheading:11045632-Animals, Genetically Modified,
pubmed-meshheading:11045632-Antigens, CD55,
pubmed-meshheading:11045632-Blood Coagulation Factors,
pubmed-meshheading:11045632-Complement C3,
pubmed-meshheading:11045632-Complement C4,
pubmed-meshheading:11045632-Complement Hemolytic Activity Assay,
pubmed-meshheading:11045632-Graft Rejection,
pubmed-meshheading:11045632-Humans,
pubmed-meshheading:11045632-Liver,
pubmed-meshheading:11045632-Liver Transplantation,
pubmed-meshheading:11045632-Papio,
pubmed-meshheading:11045632-Survival Rate,
pubmed-meshheading:11045632-Swine,
pubmed-meshheading:11045632-Time Factors,
pubmed-meshheading:11045632-Transplantation, Heterologous
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pubmed:year |
2000
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pubmed:articleTitle |
Life-supporting human complement regulator decay accelerating factor transgenic pig liver xenograft maintains the metabolic function and coagulation in the nonhuman primate for up to 8 days.
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pubmed:affiliation |
Department of Surgery, University Hospital Virgen Arrixaca, Murcia, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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