11042468

Source:http://linkedlifedata.com/resource/pubmed/id/11042468

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011065, umls-concept:C0030281, umls-concept:C0376558
pubmed:issue	9
pubmed:dateCreated	2001-3-1
pubmed:abstractText	Pancreatic beta cells are responsible for maintaining the body's glucose levels within a very narrow range; their population is dynamic, with compensatory changes to maintain euglycemia. Throughout the lifetime of a mammal, low levels of beta-cell replication and apoptosis are balanced and result in a slowly increasing mass of beta cells. The emphasis in this review is on recent insights on the natural history of the beta cell in a normal pancreas: sources of renewal, survival and changes in differentiation.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9001516
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1043-2760
pubmed:author	pubmed-author:Bonner-WeirSS
pubmed:issnType	Print
pubmed:volume	11
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	375-8
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11042468-Animals, pubmed-meshheading:11042468-Apoptosis, pubmed-meshheading:11042468-Humans, pubmed-meshheading:11042468-Islets of Langerhans
pubmed:year	2000
pubmed:articleTitle	Life and death of the pancreatic beta cells.
pubmed:affiliation	Joslin Diabetes Center, Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA. susan.bonner-weir@joslin.harvard.edu
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't