Source:http://linkedlifedata.com/resource/pubmed/id/11038653
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2000-10-25
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pubmed:abstractText |
Half-lives presented in Figure 11 summarize our findings regarding the long-term determinants of adult renal transplantation. The Figure's groups were created by cross-classifying various levels of the more important/interesting determinants identified through the multifactor analysis (Tables 1 & 2). As indicated by the black bar, half of all 16-30 year-old cadaveric kidneys transplanted into Caucasian recipients who survive beyond one year after transplantation will function for 14 years (i.e., the half-life equals 14 years). Unfortunately, in Blacks and Caucasians receiving an older donor kidney, the renal graft half-life falls to 6-8 years. When a Caucasian patient receives a spouse's kidney for transplant, the half-life increases to 17 years; when a Caucasian patient receives a HLA-matched cadaveric kidney, the half-life increases to 19 years; and, when an Asian patient receives a 16-30 year-old cadaveric kidney, the half-life jumps to 22 years. Finally, Caucasian patients receiving a HLA-identical sibling donor transplant enjoyed the greatest half-life of 26 years.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0890-9016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
341-52
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11038653-Adult,
pubmed-meshheading:11038653-African Americans,
pubmed-meshheading:11038653-African Continental Ancestry Group,
pubmed-meshheading:11038653-Age Factors,
pubmed-meshheading:11038653-Aged,
pubmed-meshheading:11038653-Aged, 80 and over,
pubmed-meshheading:11038653-Cadaver,
pubmed-meshheading:11038653-European Continental Ancestry Group,
pubmed-meshheading:11038653-Factor Analysis, Statistical,
pubmed-meshheading:11038653-Family,
pubmed-meshheading:11038653-Female,
pubmed-meshheading:11038653-Graft Survival,
pubmed-meshheading:11038653-Humans,
pubmed-meshheading:11038653-Immunosuppression,
pubmed-meshheading:11038653-Kidney Transplantation,
pubmed-meshheading:11038653-Living Donors,
pubmed-meshheading:11038653-Male,
pubmed-meshheading:11038653-Middle Aged,
pubmed-meshheading:11038653-Pregnancy,
pubmed-meshheading:11038653-Sex Factors,
pubmed-meshheading:11038653-Spouses,
pubmed-meshheading:11038653-Survivors,
pubmed-meshheading:11038653-Tissue Donors,
pubmed-meshheading:11038653-Tissue and Organ Procurement
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pubmed:year |
1999
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pubmed:articleTitle |
Determinants of long-term survival of adult kidney transplants: a 1999 UNOS update.
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pubmed:publicationType |
Journal Article
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