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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1976-1-26
|
| pubmed:abstractText |
Escherichia coli mutants deficient in DNA polymerase I, in DNA polymerases I and II, or in DNA polymerase III can efficiently and completely execute excision-repair and postreplication repair of the UV-damaged DNA at 30 degrees C and 43 degrees C when assayed by alkaline sucrose gradients. Repair by Pol I- and Pol I-, Pol II- cells is inhibited by 1-beta-D-arabinofuranosylcytosine (araC) at 43 degrees C but not at 30 degrees C, whereas that by Pol III- cells is insensitive to araC at any temperature. Thus, either Pol I or Pol III is required for complete and efficient repair, and in their absence Pol II mediates a limited, incomplete dark repair of UV-damaged DNA.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0090-5542
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5B
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
473-81
|
| pubmed:dateRevised |
2000-12-18
|
| pubmed:meshHeading |
pubmed-meshheading:1103863-Cytarabine,
pubmed-meshheading:1103863-DNA, Bacterial,
pubmed-meshheading:1103863-DNA Nucleotidyltransferases,
pubmed-meshheading:1103863-DNA Repair,
pubmed-meshheading:1103863-DNA Replication,
pubmed-meshheading:1103863-Escherichia coli,
pubmed-meshheading:1103863-Mutation,
pubmed-meshheading:1103863-Radiation Effects,
pubmed-meshheading:1103863-Ultraviolet Rays
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
DNA repair in DNA-polymerase-deficient mutants of Escherichia coli.
|
| pubmed:publicationType |
Journal Article
|