| pubmed-article:11031110 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:11031110 | lifeskim:mentions | umls-concept:C1707257 | lld:lifeskim |
| pubmed-article:11031110 | lifeskim:mentions | umls-concept:C0017428 | lld:lifeskim |
| pubmed-article:11031110 | lifeskim:mentions | umls-concept:C1416913 | lld:lifeskim |
| pubmed-article:11031110 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11031110 | pubmed:dateCreated | 2001-1-4 | lld:pubmed |
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| pubmed-article:11031110 | pubmed:abstractText | LRP1B is a novel candidate tumor suppressor gene that is inactivated by genetic and transcript alterations in nearly 50% of non-small-cell lung cancer cell lines. The gene-encoded protein is highly homologous to the gigantic lipoprotein receptor-related protein 1 (LRP1) that belongs to the family of low-density lipoprotein receptors. Using a combination of PCR-based genome walking and long-distance interexon PCR, we have determined the genomic organization of LRP1B and built a contiguous array of BAC clones spanning this gene. A total of 91 exons, varying in size from 77 bases (exon 87) to 1899 bases (exon 91), were identified in the more than 500-kb-long gene sequence. Comparative analysis of the genomic structures of LRP1B and the homologous LRP1 gene revealed a striking similarity in the location and sizes of their exons. | lld:pubmed |
| pubmed-article:11031110 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11031110 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11031110 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11031110 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11031110 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11031110 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11031110 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11031110 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:11031110 | pubmed:issn | 0888-7543 | lld:pubmed |
| pubmed-article:11031110 | pubmed:author | pubmed-author:LimC PCP | lld:pubmed |
| pubmed-article:11031110 | pubmed:author | pubmed-author:LisitsynN ANA | lld:pubmed |
| pubmed-article:11031110 | pubmed:author | pubmed-author:MuschTT | lld:pubmed |
| pubmed-article:11031110 | pubmed:author | pubmed-author:LisitsinaN... | lld:pubmed |
| pubmed-article:11031110 | pubmed:author | pubmed-author:YaklichkinS... | lld:pubmed |
| pubmed-article:11031110 | pubmed:copyrightInfo | Copyright 2000 Academic Press. | lld:pubmed |
| pubmed-article:11031110 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11031110 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:11031110 | pubmed:volume | 69 | lld:pubmed |
| pubmed-article:11031110 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11031110 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11031110 | pubmed:pagination | 271-4 | lld:pubmed |
| pubmed-article:11031110 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:meshHeading | pubmed-meshheading:11031110... | lld:pubmed |
| pubmed-article:11031110 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11031110 | pubmed:articleTitle | Genomic organization of a new candidate tumor suppressor gene, LRP1B. | lld:pubmed |
| pubmed-article:11031110 | pubmed:affiliation | Laboratory of Cancer Genetics, Department of Genetics, University of Pennsylvania School of Medicine, 422 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA. | lld:pubmed |
| pubmed-article:11031110 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11031110 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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