rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2001-1-8
|
pubmed:abstractText |
Flow cytometric, immunochemical and molecular studies were performed on leukemic blasts from a patient with minimally differentiated erythroleukemia (AML-M6v). The blasts expressed CD36 and CD71 but not lymphoid antigens, myeloid antigens, CD41 or glycophorin A. Analysis of carbohydrate antigens showed that the blasts expressed the sialyl-Tn antigen. Immunochemistry revealed that the blasts had neuron-specific enolase (NSE). Serum sialyl-Tn and NSE levels were markedly increased. Finally, an erythroid lineage was confirmed in the presence of alpha-globin messages in the blasts. Sialyl-Tn and NSE expression in leukemic blasts may be useful to identify AML-M6v.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0918-2918
|
pubmed:author |
pubmed-author:AkiokaTT,
pubmed-author:HakomoriSS,
pubmed-author:HatakeKK,
pubmed-author:IzumiTT,
pubmed-author:KiritaYY,
pubmed-author:MiuraYY,
pubmed-author:MuroiKK,
pubmed-author:NagaiTT,
pubmed-author:NakamuraMM,
pubmed-author:OzawaKK,
pubmed-author:TarumotoTT
|
pubmed:issnType |
Print
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
843-6
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:11030212-Antigens, CD,
pubmed-meshheading:11030212-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:11030212-Blotting, Northern,
pubmed-meshheading:11030212-Bone Marrow Cells,
pubmed-meshheading:11030212-Cell Differentiation,
pubmed-meshheading:11030212-Flow Cytometry,
pubmed-meshheading:11030212-Humans,
pubmed-meshheading:11030212-Leukemia, Erythroblastic, Acute,
pubmed-meshheading:11030212-Male,
pubmed-meshheading:11030212-Middle Aged,
pubmed-meshheading:11030212-Neoplasm Proteins,
pubmed-meshheading:11030212-Phosphopyruvate Hydratase,
pubmed-meshheading:11030212-Tumor Markers, Biological
|
pubmed:year |
2000
|
pubmed:articleTitle |
Sialyl-Tn- and neuron-specific enolase-positive minimally differentiated erythroleukemia.
|
pubmed:affiliation |
Department of Hematology, Center for Molecular Medicine, Jichi Medical School, Tochigi.
|
pubmed:publicationType |
Journal Article,
Case Reports
|