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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1975-12-23
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pubmed:abstractText |
The antidepressant efficacy of lithium carbonate was assessed in a double-blind trial in 23 hospitalized depressed patients. Unequivocal response was significantly more frequent in bipolar than in unipolar depressed patients. Lithium carbonate responders had a greater visual average-evoked response amplitude increase in response to increased stimulus intensity, termed "augmenting". No correlation could be demonstrated between lithium carbonate efficacy and either erythrocyte catechol-O-methyl transferase activity, age of symptom onset, number of hospitalizations, or family history of affective disorders.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-990X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1107-11
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pubmed:dateRevised |
2009-10-27
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pubmed:meshHeading |
pubmed-meshheading:1101845-Adult,
pubmed-meshheading:1101845-Aged,
pubmed-meshheading:1101845-Bipolar Disorder,
pubmed-meshheading:1101845-Brain,
pubmed-meshheading:1101845-Catechol O-Methyltransferase,
pubmed-meshheading:1101845-Clinical Trials as Topic,
pubmed-meshheading:1101845-Depression,
pubmed-meshheading:1101845-Erythrocytes,
pubmed-meshheading:1101845-Evoked Potentials,
pubmed-meshheading:1101845-Female,
pubmed-meshheading:1101845-Humans,
pubmed-meshheading:1101845-Lithium,
pubmed-meshheading:1101845-Male,
pubmed-meshheading:1101845-Middle Aged,
pubmed-meshheading:1101845-Photic Stimulation
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pubmed:year |
1975
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pubmed:articleTitle |
Lithium carbonate response in depression. Prediction by unipolar/bipolar illness, average-evoked response, catechol-O-methyl transferase, and family history.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Controlled Clinical Trial
|