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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-10-17
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pubmed:abstractText |
Neutrophil adhesion to endothelium contributes to myocardial reperfusion injury after cardiac operation. Initial neutrophil-endothelial interactions involve selectins, which bind Sialyl-LewisX on neutrophils. Blockade of selectin-mediated neutrophil-endothelial interactions with CY-1503, a synthetic analogue of Sialyl-LewisX, might reduce reperfusion injury after myocardial ischemia.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-4975
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
890-4
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11016329-Animals,
pubmed-meshheading:11016329-Animals, Newborn,
pubmed-meshheading:11016329-Endothelium, Vascular,
pubmed-meshheading:11016329-Heart,
pubmed-meshheading:11016329-Lewis Blood-Group System,
pubmed-meshheading:11016329-Myocardial Contraction,
pubmed-meshheading:11016329-Myocardial Reperfusion Injury,
pubmed-meshheading:11016329-Neutrophils,
pubmed-meshheading:11016329-Oligosaccharides,
pubmed-meshheading:11016329-Peroxidase,
pubmed-meshheading:11016329-Sheep,
pubmed-meshheading:11016329-Vasodilation
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pubmed:year |
2000
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pubmed:articleTitle |
Sialyl LewisX oligosaccharide preserves myocardial and endothelial function during cardioplegic ischemia.
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pubmed:affiliation |
Department of Cardiac Surgery, The Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
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