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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2000-10-19
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pubmed:abstractText |
To assess whether intraarticular (IA) administration of clodronate liposomes results in local macrophage depletion in patients with rheumatoid arthritis (RA). Primary goals were to address both the immunohistologic and potential toxic effects of this approach. Moreover, the correlation between immunohistologic findings and clinical assessments of disease activity and cartilage damage were assessed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1951-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11014344-Adult,
pubmed-meshheading:11014344-Aged,
pubmed-meshheading:11014344-Arthritis, Rheumatoid,
pubmed-meshheading:11014344-Biological Markers,
pubmed-meshheading:11014344-Biopsy,
pubmed-meshheading:11014344-Clodronic Acid,
pubmed-meshheading:11014344-Female,
pubmed-meshheading:11014344-Humans,
pubmed-meshheading:11014344-Immunohistochemistry,
pubmed-meshheading:11014344-Liposomes,
pubmed-meshheading:11014344-Macrophages,
pubmed-meshheading:11014344-Male,
pubmed-meshheading:11014344-Middle Aged,
pubmed-meshheading:11014344-Synovial Membrane,
pubmed-meshheading:11014344-Time Factors
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pubmed:year |
2000
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pubmed:articleTitle |
Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis.
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pubmed:affiliation |
University Hospital Nijmegen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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