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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19
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pubmed:dateCreated |
2000-10-18
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pubmed:abstractText |
Approximately 60% of patients with small-cell lung cancer (SCLC) develop brain metastases. Whole-brain radiotherapy (WBRT) gives symptomatic improvement in more than 50% of these patients. Because brain metastases are a sign of systemic progression, and chemotherapy was found to be effective as well, it becomes questionable whether WBRT is the only appropriate therapy in this situation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0732-183X
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pubmed:author |
pubmed-author:ClericoMM,
pubmed-author:CurranDD,
pubmed-author:GiacconeGG,
pubmed-author:GregorAA,
pubmed-author:GroenH JHJ,
pubmed-author:Haaxma-ReicheHH,
pubmed-author:KarnickaHH,
pubmed-author:KirkpatrickAA,
pubmed-author:LewinskiTT,
pubmed-author:PostmusP EPE,
pubmed-author:SahmoudTT,
pubmed-author:SmitE FEF,
pubmed-author:van MeerbeeckJJ
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3400-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11013281-Adult,
pubmed-meshheading:11013281-Aged,
pubmed-meshheading:11013281-Analysis of Variance,
pubmed-meshheading:11013281-Antineoplastic Agents,
pubmed-meshheading:11013281-Brain Neoplasms,
pubmed-meshheading:11013281-Carcinoma, Small Cell,
pubmed-meshheading:11013281-Combined Modality Therapy,
pubmed-meshheading:11013281-Cranial Irradiation,
pubmed-meshheading:11013281-Disease-Free Survival,
pubmed-meshheading:11013281-Female,
pubmed-meshheading:11013281-Humans,
pubmed-meshheading:11013281-Lung Neoplasms,
pubmed-meshheading:11013281-Male,
pubmed-meshheading:11013281-Middle Aged,
pubmed-meshheading:11013281-Teniposide
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pubmed:year |
2000
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pubmed:articleTitle |
Treatment of brain metastases of small-cell lung cancer: comparing teniposide and teniposide with whole-brain radiotherapy--a phase III study of the European Organization for the Research and Treatment of Cancer Lung Cancer Cooperative Group.
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pubmed:affiliation |
Departments of Pulmonary Diseases and Medical Oncology, University Hospital Vrije Universiteit, Amsterdam, the Netherlands.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Multicenter Study,
Clinical Trial, Phase III
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